About 3.45am on Wednesday April 11, two b-doubles collided while travelling in opposite directions on the Sturt Highway at Waddi.

The driver of the westbound truck, aged 32, suffered critical injuries in the crash, and was airlifted to Canberra Hospital for treatment.

He died in hospital on Thursday afternoon, April 12.

The driver of the eastbound truck, a 29-year-old man, was uninjured. He was taken to Griffith Base Hospital where he underwent mandatory blood and urine tests.

Police from Murumbidgee Police District have commenced inquiries into the crash.

A report will be prepared for the Coroner.

Emergency services received a call at 3.49am with reports two trucks had collided on the Sturt Highway about 20km East of Waddi.

The two trucks were travelling in opposite directions and scrapped past each other, resulting in one of the B-doubles ending up passenger-side down.

The single occupant male driver ended up trapped inside the cabin by confinement only, no other compression forces.

Ambulance, fire services, police and VRA rescue, and managed to extricate him out of the cabin, and he was unconscious the whole time.

The man received a critical head injury and was taken to Canberra hospital in the Southcare helicopter in a critical condition.

The other truck driver was unhurt.