Ms Ley was a member of cabinet until she resigned as health minister in early 2017 due to her Gold Coast apartment purchase controversy, but was promoted to an assistant minister when Mr Morrison became Prime Minister last August.

The 57-year-old is the longest serving female Liberal member in the House of Representatives following the retirement of former foreign minister Julie Bishop in the lead-up to the election.

Ms Ley already has more than 50 per cent of the primary vote and leads her main challenger, Albury mayor Kevin Mack, on a two-candidate preferred basis, 60.89 per cent to 39.11 per cent.

She came under fire from Mr Mack on the government's management of the Murray Darling Basin Plan, particularly the zero water allocations in the irrigation areas along the Murray River.

Ms Ley stared down her critics at a water rally in Albury's QEII Square during the campaign and still emerged victorious.

"The feeling is incredibly humbling," she said.

"There were those who said I had not put in the hard yards, that I had not worked for this community for the time I've been its local member and maybe I shouldn't be its local member any longer.

"But tonight is actually a vote of confidence I believe in me and my team.

"Politics is not about the individual, but I can't do it without the people who supported me and believed in me."

The Albury Liberal Party faithful gathered at Albury's Brewhouse in Dean Street on Saturday night and was equally buoyed by the national result.

Mr Morrison was the victim of an egg attack in Albury during the campaign with the Coalition also pledging $7.9 million to upgrade the Davey Road interchange on the Hume Freeway north of Albury.

Her long-time campaign manager Angus Macneil said Ms Ley had risen to the challenge issued by Mr Mack and his supporters.

"This is fantastic," he said.

"To do the impossible and do it with dignity which the opposition didn't have.

"No matter what they threw at her, no matter how much money they spent, the best candidate won."